Quantcast
Channel: Aurora Headlines on One News Page [United States]
Viewing all 17855 articles
Browse latest View live

AAA: Gas Prices Fall as Summer Driving Season Comes to a Close

$
0
0
AAA: Gas Prices Fall as Summer Driving Season Comes to a Close AURORA, Ill., Sept. 9, 2013 /PRNewswire/ -- Gas price averages for Illinois and Indiana are falling slightly as the summer driving season comes to an end. Illinois and Indiana drivers are currently paying, on average, $3.76 and $3.62 respectively for a gallon of regular unleaded. (Logo:... Reported by PR Newswire 1 hour ago.

Neal Notches 65 Sales In August – Reaches 600 Overall For The Year

$
0
0
Local builder records another successful sales month; hits 600th sale for 2013 with even more sales anticipated during the rest of the fall season.

Lakewood Ranch, FL (PRWEB) September 09, 2013

Neal Communities recorded 65 new home sales in August, continuing a record-setting sales year for the Lakewood Ranch-based, new home builder. This puts Neal at 600 sales for the year, with four months to go in 2013.

“As interest rates and prices continue to creep up, buyers are seeing that there is no better time to make a new home purchase,” said David Hunihan, director of sales for Neal Communities. “Our August sales numbers capped off a record breaking summer season for Neal Communities. We look forward to a strong fall season of sales, with several new communities and great options for home buyers to choose from coming soon,” said Hunihan.

Notable neighborhoods this month included Grand Palm in Venice with 13 sales, Central Park at Lakewood Ranch with 13 sales and Belleisle in Country Club East at Lakewood Ranch with seven sales. Neal also sold five homes at Boca Royale in Englewood, five at Forest Creek in Parrish, four at Fairfield in Bradenton and four at its newest neighborhood in Parrish, Sugar Mill Lakes, which recently grand opened at the end of August.

Neal Communities was named one of 2012's "America's Best Builders" by BUILDER Magazine and voted the “2013 Best Residential Builder in Southwest Florida” in a readers’ poll sponsored by Gulfshore Business Magazine. The company is ranked #1 locally by Metrostudy and by Hanley Wood Market Intelligence based on number of home sales and ranked #64 nationally among homebuilders by BUILDER Magazine. To date, Neal has built over 9,000 homes in Southwest Florida. As the area's largest and most established, locally owned and operated private builder, Neal Communities is continually striving for excellence in every aspect of the home building and development business. John Neal Homes, Neal Signature Homes, Charlene Neal PureStyle, Waterscapes Pools & Spas, and Allegiant Title Professionals all contribute to the firm's continued, record-setting local success. The company's honors and accolades include 29 Parade of Homes 2013 awards, 49 Aurora Awards, 5 Best in American Living Awards, and hundreds of local and regional industry awards. Reported by PRWeb 10 minutes ago.

Aurora bank robber who police chased, shot, gets almost 7 years

$
0
0
Derick Lamar Williams-Berrien served three years for two bank robberies, got out of prison and within two months robbed another bank and led police on a chase that ended when he was shot. Reported by Denver Post 21 hours ago.

Polar bear as big as a bus built by Greenpeace for protest parade through London

$
0
0
9 Sep 2013 20:54 The puppet polar bear, called Aurora, is sure to break the ice in London as she’s as big as a Routemaster bus PA Maybe Reported by CapitalBay 19 hours ago.

Brian Nieves, Missouri State Senator, Plans Gun Giveaway

$
0
0
A Republican state senator in Missouri is planning to give away an assault weapon during a clay pigeon shooting fundraiser next month. State Senate Majority Whip Brian Nieves (R-Washington) plans to give away a new Sig Sauer 516 Patrol AR-15 as part of his second annual clay shooting fundraiser on Oct. 12, according to a Facebook invitation for the event. Different versions of the AR-15 assault weapon were used in both last year's shooting at a movie theater in Aurora, Colo., and at Sandy Hook Elementary School in Newtown, Conn. Nieves, one of the most conservative lawmakers in the tea party-controlled Missouri state legislature, is currently pushing for lawmakers to override Democratic Gov. Jay Nixon's veto of legislation nullifying federal gun laws in the state. Nieves' fundraiser starts at $25 to attend lunch only, and costs $100 for those wanting to eat and shoot. There are also more expensive sponsorships available, according to the invitation posted on Nieves' Facebook page. The highest sponsorship is "sniper level," which costs $1,500.

$1,500 Sniper Level Sponsor: Four Shooter Packages, Six Station Sponsorships and SIX of only Fifty Chances ($100 each) at the Sig Sauer 516 PatrolAR15! (Sniper Package is a $1,900 Value!

The invite includes a note that even more discounts could be available to Second Amendment supporters.

P.S. - If you are an actual Constituent of the 26th District OR a True Blue Lover of our 2nd Amendment... You "May" be eligible for special pricing!! P.P.S.S. - Somebody will be going home from this even [sic] with a Brand New Sig Sauer 516 Patrol!! Look it up folks - It's a Top of the line AR!!

Nieves is the second Missouri lawmaker to give away an AR-15 recently. In August 2012, state Rep. John McCaherty (R-High Ridge) held a fundraiser, scheduled prior to the Colorado shooting, during which a lucky attendee was able to win the gun. Sean Soendker Nicholson, executive director of Progress Missouri, questioned Nieves' decision to do the giveaway just days before the state's gun veto vote. He noted that law enforcement officers have urged lawmakers to uphold Nixon's veto of the law, which would not allow the enforcement of federal gun laws that infringe on Second Amendment rights. "The idea that there is a sponsor level known as 'sniper' is troubling," Soendker Nicholson said. "Snipers are people killing people. It is terrifying and tragic." Nieves did not return messages left at both his legislative and campaign offices. A man listed on the Facebook invitation as "Tim" said "it is a class of sponsor" when reached by phone on Monday. When asked further questions about the giveaway, he said Nieves would be best prepared to answer them. Nieves has raised eyebrows in the past for a series of reasons, including a Facebook post in July where he called liberalism a "mental disorder." And during a bizarre April email exchange with a constituent who asked to be removed from an email list, the state senator accused the person of being in love with him. In 2010, Nieves was accused of assault by Shawn Bell, the campaign manager for the candidate Nieves defeated in the GOP state Senate primary. Nieves denied the accusation, and the Franklin County prosecutor did not file criminal charges, citing a lack of evidence. Reported by Huffington Post 18 hours ago.

Seattle DOT fixes $5,000 bus-lane mistake

$
0
0
The Seattle Department of Transportation says it painted “Bus Only” markings in the wrong place on a stretch of Aurora Avenue North, in preparation for the RapidRide E line to launch in Feburary. The department acknowledged the mistake last week and said it would cost $5,000 to remove&nb Reported by Seattle Times 16 hours ago.

Colorado state senate recall votes are a test for Bloomberg

$
0
0
The mayoral primary isn’t the only election Mayor Bloomberg is watching Tuesday. Residents in two Colorado districts are voting on an effort to recall a pair of state senators who voted for a tough new Colorado gun law in the wake of mass killings in Aurora, Colo., and Newtown, Conn. — and Bloomberg has personally put up $350,000 to help keep them in office. Reported by NY Daily News 14 hours ago.

Missouri Sen. Brian Nieves Will Give Away Assault Weapon During Fundraiser

$
0
0
Missouri Sen. Brian Nieves Will Give Away Assault Weapon During Fundraiser Culture
Legal
Lifestyle
Local
Politics

A Republican state senator from Missouri plans to give away an assault rifle during a fundraiser he is hosting in October. Sen. Brian Nieves will be handing out a new Sig Sauer 516 Patrol AR-15 on the second day of the “2nd Amendment Sporting Clays Fundraiser.” Different models of the AR-15 were used during the massacre at Sandy Hook Elementary School and the movie theater shooting in Aurora, Colo. Nieves wants Missouri lawmakers to override Gov. Jay Nixon's veto of legislation nullifying federal gun laws in the state, The Huffington Post reported.

According the to event’s Facebook page, there are a number of different gun-themed sponsorship opportunities that are available, including "sniper level" sponsorship which costs $1,500.

Here’s the complete list:

$150 Station Sponsor: Signage at Shooting Stations (similar to hole sponsor in golf tourney)

$250 Beverage Sponsor: Prominent Advertising of Company or Entity in Beverage Area

$500 Lunch Sponsor: Prominent Advertising of Company or Entity throughout Lunch Area.

$750 Sharp Shooter Event Sponsor: Four Shooter Packages & Three Station Sponsorships. (Sharp Shooter Packages is an$850 Value!)

$1,000 Marksman Event Sponsor: Four Shooter Packages, Four Station Sponsorships and THREE of only Fifty Chances ($100 each) at the Sig Sauer 516 Patrol AR15! (Marksman Package is a $1,300 Value!)

$1,500 Sniper Level Sponsor: Four Shooter Packages, Six Station Sponsorships and SIX of only Fifty Chances ($100 each) at the Sig Sauer 516 PatrolAR15! (Sniper Package is a $1,900 Value!

The online invite also includes a note alerting Second Amendment supporters about discount deals and the gun giveaway.

P.S. - If you are an actual Constituent of the 26th District OR a True Blue Lover of our 2nd Amendment... You "May" be eligible for special pricing!!

P.P.S.S. - Somebody will be going home from this even [sic] with a Brand New Sig Sauer 516 Patrol!! Look it up folks - It's a Top of the line AR!!

Nieves failed to respond to calls to his legislative and campaign offices.

Sources: The Huffington Post, Inagist

1 Reported by Opposing Views 4 hours ago.

New Mid-Core Mobile and Social Games to be Launched by Renatus Media

$
0
0
Renatus Media, a leading US game publisher to bring new mobile and social games to mid-core audience this fall.

Palo Alto, California (PRWEB) September 10, 2013

With this year’s boost in the mid-core gaming segment, gamers are seeking more engaging play, a more complex environment and, at the same time, something less time-consuming than hard-core games. Renatus Media, one of the leading game publishers in the US, is scheduled to release a number of new social and mobile games beginning in September to target this growing audience.

During the previous 12 months, Renatus gained recognition among players of casual games with its highly engaging portfolio of social casino and arcade titles. The new mid-core games follow Renatus’ August release of Brave Tales on Facebook, its entrée in the mid-core gaming segment.

In Brave Tales, gamers experience a mix of RPG (role-playing game) and strategy with unique game mechanics. They are encouraged to fight the enemy using a variety of characters as they navigate through primeval woods inhabited by dangerous predators, barbarians and other deadly creatures. Brave Tales is available on Facebook (https://apps.facebook.com/bravetales).

This autumn Renatus will release several mid-core games including:·     Nuclear Farm: Aurora (Facebook)
·     Undersky: the Eternal Saga (iOS, Android and Windows Phone)

Mark Watt, Renatus’ President commented, “Renatus has an incredibly exciting pipeline of mid-core games to address the growing demand in this sector. Our combination of unique game play, compelling storylines and captivating action will delight gamers. We have very high hopes for our mid-core success.”

In Nuclear Farm: Aurora, the first to go live in early September, the main character will be forced to survive in the post-apocalyptic conditions of a global nuclear war that either destroyed or mutated most living creatures on earth. Survivors must learn how to collect rare resources, produce food and protect themselves from monsters.

For more information, visit http://renatus.com/.

Contact:
Mark Watt
President
Renatus Media, LLC
pr(at)renatus(dot)com
+1 (650) 391-9758

About Renatus Media, LLC
Renatus Media, LLC, is a leading publisher of mobile and social games on the global market. The company is based in Palo Alto, California, US. In operation since 2012, Renatus has already gained 10 million monthly active users on iOS, Android and Facebook, established cooperation with 10 game development studios from Eastern Europe (Ukraine, Russia, Belarus) and published nearly 30 game titles.

Renatus provides game developers with all-in-one publishing services, including testing, analytics, monetization improvement, game launch, marketing strategy implementation. Reported by PRWeb 1 hour ago.

Chicago Heat Wave Prompts More Area School Closures As High Expected To Reach 98 Degrees

$
0
0
It's going to be another scorcher in the Chicago area Tuesday, prompting several school officials to cancel classes or end the day early for the second time in just two weeks. After a muggy Monday with highs in the mid-90s, Tuesday's temps are expected to hit 98 degrees in Chicago with heat indices ranging from 95 to 100 degrees in the metro area.

Post by US National Weather Service Chicago Illinois.
Despite the simmering heat, Chicago Public Schools remain open Tuesday -- a move that's drawn criticism from those noting many CPS buildings are without air conditioning. Exactly how many? For the record, CPS said last month they don't exactly know.



Record heat, schools with no AC in #cps, thinking of those teachers, students and learning conditions. Can't imagine.

— Autumn Laidler (@MsLaidler) September 10, 2013


During the heat-wave two weeks prior, a CPS spokesman sent HuffPost the following on the district's heat protocol:

"In cases where schools do not have air conditioning, principals are following protocols to help keep their schools as comfortable as possible and are utilizing among 800 fans that CPS is making available at their request," while adding, "We are finalizing and updating the total number of schools that do not have air conditioning, but the majority of schools in the district have full or partial A/C in the school."

According to the district's Department of Operations protocol, outdoor temperatures between 85-95 degrees are not considered to be in the "dangerous" range. A handful of private schools in the city closed or are ending the day early, like St. Francis de Sales High School in the South Deering neighborhood. In the suburbs, 20 schools kept their doors closed Tuesday over lack of air conditioning. ABC Chicago reports the schools include districts in Waukegan, Naperville, Aurora, Bolingbrook and Plainfield. Some area parents have pushed to have the school year start later if buildings can't be properly equipped with air conditioning. As the Associated Press reports, "heat days" are becoming almost as common in Midwest schools as snow days. Both Chicago and Rockford could break high temp records Tuesday. CBS 2 meteorologist Megan Glaros reports 95 degrees is the Sept. 10 record set in 1983. "The unseasonable hot weather will linger one more day," said the National Weather Service, noting a cold front moving in will cool area temperatures by week's end. As always, Chicago residents can visit cooling centers at Department of Human Services locations. Reported by Huffington Post 44 minutes ago.

iLuv Introduces Stylish and Unique Cases for the Launch of the New iPhone 5C

$
0
0
Enhance and Protect the iPhone 5C with Quality Cases from iLuv

Port Washington, NY (PRWEB) September 10, 2013

iLuv Creative Technology, the premier provider of the most comprehensive line of accessories for the mobile lifestyle, announces today their new line of fashionable and protective cases for the anticipated launch of the iPhone 5C. iLuv’s new line boasts cases for every mobile lifestyle and features protective designs that range from sleek and professional to creative and fun.

“Whenever Apple makes an announcement, consumers are eager to be among the first to get their hands on the new device,” said Jason Park, Marketing Manager at iLuv. “And while they want to be among the first to own the device itself, they also want to dress it up and protect it with high-quality accessories that reflect their personal sense of style. We strive to be first-to-market with a complete lineup of stylish cases and useful accessories for the new iPhone 5C because even lower cost options for mobile devices like the iPhone 5C need to be ensured complete protection and ease-of-use.”

The new line of iPhone 5C cases expands on the current line of cases by offering many of the classic iLuv designs everyone knows and loves while adding an abundance of fresh designs and styles.

New case and accessory designs include the following:

Vyneer
Dual material protection case· Polycarbonate shell with TPE frame around corners and edges
· Translucent base shows off the iPhone’s beauty
· Soft TPE frame protects corners and edges from dings, scratches and dents
· Wide opening in the bottom to accommodate all ports, and a variety of earphone plugs and cables

La Pedrera
Artistic 3D effect hardshell case· Antoni Gaudi inspired design
· 3D sculpted polycarbonate (PC) shell
· Visual openings in case to allow device to shine through

Aurora Illusion
Glow-in-the-dark case· Find your iPhone in the dark
· Playful pattern illuminates at night or in black light
· Silicone case provides snug fit and protection
· Laser-etched lightweight design with enhanced grip

Diary
Premium wallet case· Made with premium, PU leather
· Two slots for credit cards
· Polycarbonate interior shell securely holds iPhone
· Superior 360-degree protection
· Allows users to answer calls and keep the screen cover closed

Snoopy Series
Hardshell case· Playful, exclusive iLuv Peanuts® design
· New designs featuring Snoopy’s fashionable sister Belle
· Super-sleek, customized fit provides direct access to iPhone controls
· Durable hardshell construction
· In-mold labeling graphics with smooth, coated finish

Pricing and Availability
iLuv’s complete line of iPhone 5C Series cases and accessories are available at http://www.iLuv.com. Prices range from $9.99-$29.99.

Follow us on Twitter @iLuv_World, Facebook at iLuv Creative Technology, Instagram at iLuv_Creative_Technology, and Pinterest at iLuv Creative Technology.

About iLuv
iLuv Creative Technology, the premier provider of the most comprehensive line of accessories for Apple, Samsung and Smartphone devices, rapidly delivers products for today’s discriminating consumers. Since inception, iLuv has amassed a total of 35 prestigious awards including 6 red dot product design awards, 4 prestigious iF Design Awards, 2 Good Design Awards, and 23 CES Innovation Awards. iLuv was also recognized with 1 Global iBrand Top 20 award. These awards serve as recognition for our innovative design and engineering across a range of mobile accessories, including headphones, adapters, speakers and chargers. Headquartered in New York, iLuv is a division of jWIN Electronics Corp., a leading consumer electronics company since 1997. All iLuv products are conceived, designed and developed in New York and continue to lead in quality, value, design and innovation. Learn more about our distinctive range of products and why iLuv means Innovative Lifestyle Unquestionable Value® at http://www.iLuv.com.

iLuv® and Innovative Lifestyle Unquestionable Value® trademarks are the exclusive properties of jWIN Electronics Corp. and are registered with the U.S. Patent and Trademark Office, and may be registered or pending registration in other countries. All other iLuv® trademarks, service marks, and logos may be registered or pending registration in the U.S. or in other countries. All other trademarks or registered trademarks are the property of their respective owners. © 2013 iLuv Creative Technology. Reported by PRWeb 22 hours ago.

Protect Your New iPhone 5S with iLuv’s Stylish and Multifunctional Cases

$
0
0
iLuv is first-to-market with line of accessories for Apple’s newest device.

Port Washington, NY (PRWEB) September 10, 2013

iLuv Creative Technology, the premier provider of the most comprehensive line of accessories for the mobile lifestyle, introduces their new line of premium accessories for the highly-anticipated iPhone 5S. All of the newly-designed iLuv cases will provide consumers with a fresh and diverse new range of options in materials, styles and price points when they are looking to express their individual sense of style in their mobile device cases.

"iLuv not only strives to be first-to-market with cases for the latest Apple products, but we also aim to provide a wide range of innovative, high-quality and fashionable accessories to give consumers everything they want and need in their cases,” said Jason Park, Marketing Manager at iLuv. “Our new line combines multifunctional elements with everything from current fashion trends to timeless designs to offer a case for every mobile lifestyle. These new cases not only bring style and protection to the iPhone 5S, but also add value to Apple’s newest device."

The new line of iPhone 5S cases includes classic iLuv designs everyone knows and loves while adding an abundance of new designs, including cases that are inspired by famous works of art and beloved Peanuts characters.

Flightfit Gaudi
Artistic 3D glow-in-the-dark case
•Fused two-layer construction of sandblasted PC and soft TPE interior
•Intelligently designed structure to maximize protection while eliminating bulk
•Glow-in-the-dark pattern illuminates at night or in black light
•Guards your device with double protection
•Customized to fit securely on your iPhone
•Maintains access to all ports and controls
•Available in fun colors to suit your style

Vyneer
Dual material protection case
•Polycarbonate shell with TPE frame around corners and edges
•Translucent base shows off the iPhone’s beauty
•Soft TPE frame protects corners and edges from dings, scratches and dents
•Wide opening in the bottom to accommodate all ports, and a variety of earphone plugs and cables

La Pedrera
Artistic 3D effect hardshell case
•Antoni Gaudi inspired design
•3D sculpted polycarbonate (PC) shell
•Visual openings in case to allow device to shine through

Jstyle Runway
Full grain leather wallet case for women
•Crafted from full-grain, top-grade leather with saffiano finish
•Holds everything you need inside: cash, cards and iPhone
•Provides 360-degree protection from impact and scratches
•Never lose your iPhone again
•Includes a wrist strap and interior zip pouch

Tangle
Woven elastic case
•Rigid TPU frame to hold and protect your iPhone securely
•Elastic gore strips can be stretched from case to hold a stylus, cables, earphones, etc.
•Fashionable protection in bright colors

Aurora Illusion
Glow-in-the-dark case
•Find your iPhone in the dark
•Playful pattern illuminates at night or in black light
•Silicone case provides snug fit and protection
•Laser-etched lightweight design with enhanced grip

Snoopy 3D
Artistic 3D effect silicone case
•3D sculpted flexible shell
•Raised design allows the character to come to life
•Fashionable, fun colors
•Convenient wrist strap

Belle 3D
Artistic 3D effect silicone case
•3D sculpted flexible shell
•Raised design allows the character to come to life
•Clever graphics have Belle kissing you while you’re on the phone
•Fashionable, fun colors

Pricing and Availability
iLuv’s complete line of iPhone 5S Series cases and accessories are available at http://www.iLuv.com. Prices range from $9.99-$79.99.

Follow us on Twitter @iLuv_World, Facebook at iLuv Creative Technology, Instagram at iLuv_Creative_Technology, and Pinterest at iLuv Creative Technology.

About iLuv
iLuv Creative Technology, the premier provider of the most comprehensive line of accessories for Apple, Samsung and Smartphone devices, rapidly delivers products for today’s discriminating consumers. Since inception, iLuv has amassed a total of 35 prestigious awards including 6 red dot product design awards, 4 prestigious iF Design Awards, 2 Good Design Awards, and 23 CES Innovation Awards. iLuv was also recognized with 1 Global iBrand Top 20 award. These awards serve as recognition for our innovative design and engineering across a range of mobile accessories, including headphones, adapters, speakers and chargers. Headquartered in New York, iLuv is a division of jWIN Electronics Corp., a leading consumer electronics company since 1997. All iLuv products are conceived, designed and developed in New York and continue to lead in quality, value, design and innovation. Learn more about our distinctive range of products and why iLuv means Innovative Lifestyle Unquestionable Value® at http://www.iLuv.com.

iLuv® and Innovative Lifestyle Unquestionable Value® trademarks are the exclusive properties of jWIN Electronics Corp. and are registered with the U.S. Patent and Trademark Office, and may be registered or pending registration in other countries. All other iLuv® trademarks, service marks, and logos may be registered or pending registration in the U.S. or in other countries. All other trademarks or registered trademarks are the property of their respective owners. © 2013 iLuv Creative Technology. Reported by PRWeb 22 hours ago.

Study: Redefining the Criteria for ALK Positive Lung Cancer

$
0
0
A University of Colorado Cancer Center study published today in the journal Cancer shows that the current criteria used to match lung cancers with the drug crizotinib may miss some patients who could benefit from the drug.

Aurora, Colo. (PRWEB) September 10, 2013

A University of Colorado Cancer Center study published today in the journal Cancer shows that the current criteria used to match lung cancers with the drug crizotinib may miss some patients who could benefit from the drug. The findings suggest that doctors should look closer at borderline or atypical ALK-negative cases, and could widen the population of lung cancer patients offered treatment with crizotinib or other ALK-inhibitor drugs.

ALK stands for anaplastic lymphoma kinase, a gene that is turned off in most adult tissues in the body, but which can be re-activated to cause cancer when it is fused with another nearby gene. The original and still most widely-used test for ALK-positive lung cancer was co-developed by Leila Garcia, PhD, director of the Cytogenetics Core Resource at the University of Colorado Cancer Center. The test uses the technique known as fluorescence in situ hybridization (FISH) to test for the fusion of the ALK gene with another gene that turns ALK back on, allowing it to drive some lung cancers. When a cancer is ALK positive it can be very effectively treated with crizotinib, a targeted anti-ALK drug.

"The test is fairly definitive – either a cell is ALK positive or not using the criteria we initially implemented. However, what is less certain is the exact percentage of ALK-positive cells required to label an entire tumor as ALK-positive. Is there an exact threshold of ALK-positive cells that will make a patient respond to crizotinib or other ALK inhibitors?" Garcia says.

“Since the beginning we have looked at the cells in a tumor and if 15 percent or more of these cells show the changes classically associated with an ALK rearrangement, we classify that tumor as ALK-positive and offer treatment with crizotinib," says Ross Camidge, MD, PhD, investigator at the CU Cancer Center and director of the thoracic oncology clinical program at University of Colorado Hospital.

Previous studies indicated that this 15-percent point fell in a clear gap between tumors that were obviously ALK-positive and tumors that were obviously ALK-negative, making it an attractive threshold.

"But what this study shows is that when you look not at tens, but hundreds of cases, tumors clearly exist that come right up to the 15-percent cutoff point," Camidge says.

Another possible gray area is when a gene rearrangement occurs but is very complex – like shuffling cards rather than just cutting the deck. In this situation the typical separated dot pattern indicative of ALK rearrangement may not be present, but instead doublets or triplets of single or un-separated dots may exist. This atypical cellular footprint can tell an expert that, while officially ALK-negative, the cancer has made some changes in the region of the ALK gene that could still make the cancer sensitive to ALK-inhibitor drugs.

“We believe these data suggest that such borderline and atypical negative cases deserve a closer look, perhaps with new kinds of diagnostic tests," says Camidge.

The current study tested 1426 samples of non-small cell lung cancer, which included 174 officially positive for an ALK rearrangement and 1252 that were officially negative. Of the ALK-negative tumors, 121 had greater than 10 percent ALK-positivity, but were still below the 15 percent needed to classify the overall tumor as ALK-positive. This means that 8.5 percent of non-small cell lung cancers were "borderline" negative. In the study, 1-2 percent also showed atypical-negative patterns, a group that may also benefit from a closer re-evaluation of their ALK status.

Early in 2013, serendipity provided a chance to test whether at least one of the Colorado team’s hypotheses were correct. In a case described in an upcoming article in the Journal of Thoracic Oncology, Dr. Shengxiang Ren from the Shanghai Pulmonary Hospital describes a patient who traveled halfway across the world for a second opinion at the University of Colorado, where much of the research leading to ALK-targeted drugs has taken place.

“We were thrilled this patient had sought out an opinion from one of the leading centers in lung cancer and could not have been happier with the collaboration that developed,” Ren says.

The patient was originally classified ALK-negative using the standard FISH assay. However, Dr. Garcia recognized that an atypical negative pattern was present. One way of looking closer at ALK uses the technique of immunohistochemistry (IHC), which looks directly for the protein the aberrant ALK gene creates. Using an IHC assay for ALK conducted within the laboratory of Fred R. Hirsch, MD, PhD, associate director for international programs at the CU Cancer Center, the team quickly confirmed that the patient’s tumor was making the ALK protein and should really be considered ALK-positive. Another test called RT-PCR conducted in Shanghai on the same specimen looked at the ALK gene in a third way, confirming the presence of messages coming from the gene that were telling the cell to make the abnormal protein.

"Amazingly, crizotinib was being licensed in China the following week and so we simply wrote the patient a prescription and sent him back to Dr. Ren in Shanghai, where his latest scans show he is responding beautifully to the drug," Camidge says. "All of the early work on ALK positive lung cancer has really helped to clarify what can be achieved by personalized medicine, but we have to keep pushing the envelope to maximize this approach in routine cancer care. For ALK-positive lung cancer, basically our goal now is to make sure that everyone who could benefit from an ALK inhibitor gets an ALK inhibitor."

The CU Cancer Center’s Thoracic Oncology Program is world renowned for its pioneering treatment of lung cancer. The program includes a multidisciplinary team of specialists and subspecialists working together to establish the best treatment plan for each patient. Advanced molecular profiling of a patient’s tumor, combined with an extensive array of standard and experimental treatments available through clinical trials has led to major advances in patient outcomes in the last few years.

The program’s one-year survival rates for advanced lung cancer consistently run twice as high as the national average. The survival rates at five years run four times higher than the national average. Additionally, the Center’s new Remote Second Opinion Program now offers access to program experts for patients who prefer not to travel.

Please consider supporting the Lung Cancer Colorado Fund. This unique fund is overseen by the physicians and scientists and supports all aspects of the CU Cancer Center’s and University of Colorado Hospital’s combined fight against lung cancer.

For an appointment with a University of Colorado physician, please contact Bethie Jean Philippe (720-848-3386), intake coordinator for the lung cancer program.

This work was supported by the University of Colorado Lung Cancer Specialized Programs of Research Excellence (SPORE) grant P50CA058187 and by the University of Colorado Cancer Center Shared Resources CCSG P30CA046934. Reported by PRWeb 22 hours ago.

Guns and kids: the youngest casualties of America's infatuation with firearms | Ana Marie Cox

$
0
0
Dear NRA, are you really going to tell me that 'guns don't kill children; children kill children'?

The cover of the recent Children's Defense Fund report (pdf) on gun violence in the United States carries a single statistic:



The number of children and teens killed by guns in one year would fill 134 classrooms of 20 students each.



That's just a more dramatic way of stating an already staggering figure – 2,694 in 2010. Most of the report's 73 following pages are devoted to restating it. Sometimes, this done to illustrate the chilling frequency of such deaths:

• One child or teen died every 3 hours and 15 minutes
• Seven children and teens died every day, more than 20 every three days
• Fifty-one children and teens died every week

Other times, the same set of statistics (all from the Centers for Disease Control) is used to drive home the magnitude of the tragedy, relating it to the kinds of violence we think we understand:



Nearly three times more children and teens were injured by guns in 2010 than the number of US soldiers wounded in action that year in the war in Afghanistan; 82 children under five died from guns in 2010, compared to 55 law enforcement officers killed in the line of duty.



And then, there's the shameful comparison to other countries:



US children and teens are 17 times more likely to die from a gun than their peers in 25 other high-income countries combined.



Put it slightly differently:



US children and teens made up 43% of all children and teens in these 26 countries but were 93% of all children and teens killed by guns.



The report is an exercise in word problem reformatting, a hideous nightmare of a standardized test in which every answer is both "all of the above" and wrong. We have failed. The numbers in the examples change, but the fact they illustrate is big and ugly and refuses cosmetic adjustment: the United States, despite a meekly gratifying downward trend, continues to kill its young people with guns at rate more in line with war-torn nations than the prosperous, peaceful countries we presume to lead. In a different, but equally upsetting report, the World Health Organization observed (pdf):



With the notable exception of the United States, most countries with youth homicide rates above 10 per 100,000 are either developing countries or countries caught up in the turmoil of social and economic change.



The repetitiveness of the statistics reflects desperation, I think. One can picture the authors' frantic oneupmanship in coming up with ways to make the truth as vivid as possible: compare it to war! Compare it to Sandy Hook! And, of course, show us the victims – not via pictures of the violence itself, thank God, but in descriptions of who they were: post-Sandy Hook stories salt the wound:

Steven Curtis, 12, dead after accidentally shooting himself in the head with his father's gun. Caroline Sparks, 2, shot in the chest and killed by her five-year-old brother. Tayloni Mazyck, 11, caught in gang crossfire and paralyzed for life. The list goes unrelentingly on. (As of July, the New York Daily News found 120 children had been killed by gunfire since Sandy Hook; they relied only on news reports, not CDC surveys. The end number will be undoubtedly, horrifyingly larger.)

The report wallops us over the head with statistics because its authors can't reach through the pages and throttle us. The frustration is as understandable as it is evident, for as gruesome as the statistics about violence are, the recounting of what legislation has and has not passed is even more dispiriting. Over and over, the public's willingness (even eagerness) to tighten gun laws has been outmatched by the cowardice of politicians in mysterious thrall to the National Rifle Association.

The whimpering death of the Toomey-Manchin bill has been examined at length; the CDF notes further that, beyond the Senate voting against regulations, a majority of Americans were for (assault weapons ban, background checks):



Several proposals to weaken existing gun violence prevention measures received more 'Yes' votes than the background checks provision. They included a concealed-carry reciprocity proposal and a provision to prevent veterans who are mentally incapacitated from losing their right to own a gun without a court hearing.



The news gets worse as we get closer to home, where state legislatures reacted to Sandy Hook primarily by widening access to firearms and weakening regulation. You read that right: more states passed pro-gun legislation in the wake of Sandy Hook than there were states that passed stricter gun control. Maryland, Connecticut and New York and New Jersey all tightened gun laws; Utah, Virginia, Kentucky, West Virginia, Oklahoma, Mississippi, North Carolina, Indiana, Louisiana, Arkansas, South Dakota, and Kansas all somehow relaxed their gun laws – by extending the number of places one can carry a concealed weapon, by allowing guns in schools, by instituting "stand your ground" laws, or adding the right to own a firearm to the state constitution.

Colorado reigned in some gun rights after the Aurora massacre in July 2012; today, it is at the center of an NRA-sponsored recall, to be decided this week. Another state legislature, Missouri, both liberalized conceal carry and took unprecedented step of nullifying all federal gun laws – outlawing the federal government from enforcing its gun restrictions within the state. The bill was passed and then vetoed. This week, the legislature will meet in a special session to override the veto.

The Missouri proposal goes beyond the kind of passive quasi-civil disobedience of, say, medical marijuana laws, or even those rebellious legislatures that have sought to nullify Obamacare. The Missouri law would punish federal enforcement of legally enacted statutes by setting criminal penalties for federal agents, and prohibiting state officials from co-operating with federal efforts.

This is insanity.

Conservatives and liberals alike can use the tragedy of children's deaths as evidence of the need for their favored policies. After all, gun rights advocates want more guns in schools, they argue, for the greater safety of the children. They might even deny the relevance of concealed-carry laws and stand-your-ground provisions to the issue at hand. What does banning raids from the federal government's "jackbooted thugs" (in NRA president Wayne LaPierre's famous formulation) have to do with those classrooms full of dead kids?

There is only a shuddering half-step between between the general availability of firearms, their lax regulation, and the death of children. States with background checks have 16% lower gun fatality rates. Child access prevention laws reduce accidental shootings by as much as 23%. Australia passed a strict assault weapons ban and mandatory buy-back program (the US law once on the books had no such program) in 1996 – and hasn't had a single mass shooting since.

I'm not even sure the CDF believed this report would change that many minds: to anyone disinclined to believe that strict gun laws work, the report is just a recitation of bad things happening because of bad guys (even if a lot of those "bad guys" are other children). Perhaps the point of the report was more modest: just to let people know what is happening, what violence is going on beneath surface, as politicians and lobbyists posture. Though, who knows: Missouri has the fourth most gun deaths in the nation, the sixth most deaths by firearm for children under 18 and is a favorite transit point for gun-traffickers (in a July raid that may be deemed illegal next week, federal agents seized 267 illegal weapons) and look what's happening there.

We're beyond the point of "what will it take" when it comes to sane gun laws. The tragedies that should spur protests and marches and petitions happen quietly every day. Reported by guardian.co.uk 20 hours ago.

Colorado Recall Campaigns Push To Turn Out Voters

$
0
0
By COLLEEN SLEVIN, THE ASSOCIATED PRESS

DENVER — Campaigns were working to get as many voters as possible to the polls in Colorado's first legislative recalls on Tuesday, elections that tested popular support for gun limits in a state with a strong tradition embracing Second Amendment rights.

The National Rifle Association and New York Mayor Michael Bloomberg lined up on opposite sides of the recalls for Senate President John Morse in Colorado Springs and Democrat Sen. Angela Giron in Pueblo.

Both legislators voted for 15-round limits on ammunition magazines and for expanded background checks on private gun sales after the 2012 mass shootings in Aurora and Newtown, Conn. The legislation passed Colorado's Democrat-led Legislature this year without any Republican support and was signed into law by Democratic Gov. John Hickenlooper.

Reported contributions to Morse and Giron totaled about $3 million, dwarfing the amount raised by gun activists who petitioned for the recall, though some independent groups didn't have to report spending. Both the NRA and Bloomberg contributed more than $300,000 to the pro- and anti-recall campaigns.

Besides being the latest chapter in the national debate over gun rights, the recalls also exposed divisions between Colorado's growing urban and suburban areas and its rural towns. Dozens of elected county sheriffs have sued to block the gun laws and some activists are promoting a largely symbolic measure to secede from the state.

One of the Morse recall organizers, Timothy Knight, said supporters are upset that lawmakers limited debate on the gun legislation and seemed more inclined to take cues from the White House than their constituents.

"If the people had been listened to, these recalls wouldn't be happening," Knight said.Unlike most recent elections, there are no automatic mail ballots, so voters need to cast their ballots in person.

"This is a good, old-fashioned knock and drag operation – knocking on doors and dragging them to the polls," said Colorado Democratic Party chairman Rick Palacio, who was working in Giron's Pueblo County district on Tuesday.

Republican turnout was stronger in early voting in Morse's district in El Paso County but Democrats narrowed the GOP advantage though mid-afternoon on election day. In Giron's district, Democrats have been outpacing Republicans at the polls. Both districts also have a significant number of unaffiliated voters and guns are not strictly partisan issue in the state.

Hickenlooper initially rejected calls for stronger gun control laws after 12 people were killed and 70 injured in an Aurora movie theater in July 2012. The governor changed his mind right before the December 2012 Newtown massacre, in which a gunman killed 20 children and six women at Sandy Hook Elementary School.

Hickenlooper kept a low profile in the recalls. A recent statewide poll by Quinnipiac University suggested that 52 percent of voters disapproved of Hickenlooper's gun policy while 35 percent approved.

A former police chief in suburban Colorado Springs, Morse said Colorado's gun laws were commonsense ideas to reduce fatalities in mass shootings. He was first elected to the Senate in 2006, defeating a Republican incumbent in a competitive district. His term expires in 2014, and he insists he wants no other political office.

Giron was first elected in 2010 in a heavily Democratic district. She oversaw the Senate committee that first approved the measure to require background checks on most private and online gun sales. Giron also voted for the new 15-round limits on most ammunition magazines.

Challenging Morse in Colorado Springs was former Republican Councilman Bernie Herpin. In Pueblo, former police officer George Rivera challenged Giron. Reported by Huffington Post 17 hours ago.

Colorado Recall Results: Senate President John Morse Defeated In Major Victory For NRA

$
0
0
WASHINGTON -- The first recall election in Colorado's history on Tuesday marked a major victory for the National Rifle Association and gun rights activists, with the ouster of state Senate President John Morse (D-Colo.). The fate of another Democrat facing recall, state Sen. Angela Giron of Pueblo County, was unclear at press time. The two lawmakers were the target of separate recall fights over their support for stricter gun laws earlier this year.

"The highest rank in a democracy is citizen, not senate president," Morse said in his concession speech, as his supporters solemnly watched, some shedding tears.

What originally began as local political fallout over the Democratic-controlled legislature's comprehensive gun control package quickly escalated into a national referendum on gun policy. Morse and Giron both voted in favor of the legislation, signed into law by Gov. John Hickenlooper (D) in March, which requires background checks for all firearm purchases and bans ammunition magazines over 15 rounds.

Gun rights activists initially sought to recall four Democrats they perceived as vulnerable, but only collected the required signatures to challenge Morse and Giron.

Language for the "yes" ballots, authored by proponents of the recall, said the lawmakers were guilty of contempt for "the constitutional liberties of the people" and "firearm manufacturers and for the rights of Colorado citizens." Those working against the recall used the "no" ballots to cast their opponents as "extremists" who were willing to make guns available to felons and "spouse abusers."

While voter turnout is typically low in recall elections, Democrats accused pro-recall activists of engaging in voter suppression tactics. A big blow to Morse and Giron was a ruling that prohibited voting by mail in the election, even though Colorado voters have overwhelmingly relied on mail-in ballots in the past. The decision ignored a state law passed earlier this year that guaranteed a ballot by mail to every registered voter in Colorado, including in a recall election.

A get-out-the-vote canvasser for Giron, who requested anonymity out of safety concerns, said gun rights activists also engaged in "extreme voter intimidation" at polling centers in Pueblo on Tuesday.

"We had to call the police on a van of four huge guys staking out our staging location," the canvasser told HuffPost. "Volunteers are being followed, threatened, having their pictures taken and yelled at. We're now being told that it's bad enough to call 911 immediately."

Lawmakers and advocates across the country eagerly awaited Tuesday's results, which many felt carried significant implications for the national debate on gun policy following December's mass shooting at Sandy Hook Elementary School in Newtown, Conn. In April, the United States Senate failed to pass a measure to expand background checks, spurring anti-gun violence groups to mount a campaign to match the intensity of the NRA and to promise political retribution for the senators who voted against stricter gun laws.

This national focus meant outside spending reached unprecedented levels in the Colorado recall, with both sides viewing the election as must-win.

New York City Mayor Michael Bloomberg, a staunch supporter of stricter gun laws, donated $350,000 to Morse and Giron. Billionaire philanthropist Eli Broad gave a separate $250,000 check to help the legislators, while Sen. Kirsten Gillibrand (D-N.Y.) repeatedly issued fundraising calls for Giron in emails to her supporters. The Denver Post reported Monday that those in Morse and Giron's corner had collected nearly $3 million, while proponents of the recall raised about $540,000.

"One thing is clear from the Morse defeat: Mike Bloomberg is political poison," NRA spokesman Andrew Arulanandam said in a statement.

The NRA spent heavily on the recall effort, reporting at least $360,000 and funneling unspecified dollars through its nonprofit arm. The billionaire conservative Koch brothers also entered the fray, using their advocacy group Americans For Prosperity to target Morse and Giron. Due to the organization's nonprofit status, AFP also did not have to report its spending to the Federal Elections Commission.

In an interview with HuffPost last month, Giron acknowledged that the recall's outcome could send "reverberating messages to legislatures across the country." But she said the vast amount of money being spent by both sides underscored that the election had developed a much broader focus than gun policy.

"I think it's a lot about Democrats vs. Republicans, and has grown very partisan," she said.

Indeed, the Koch brothers' involvement had little to do with guns, and AFP primarily focused its attacks against Morse on other issues that made him a vulnerable target in his conservative-leaning district. The group distributed fliers and doorhangers likening Morse to Bloomberg on virtually every issue except guns, instead concentrating on issues like taxes and health care.

One coalition of Colorado Springs law enforcement officials even took advantage of the recall effort to go after Morse for touting his experience as a former police officer in his campaign ads. The group endorsed Morse's recall, citing its opposition to his votes on sentencing for convicted criminals and legislation he sponsored to soften prison terms and limit the number of people who could be incarcerated in state prisons.

Colorado's history on gun rights has long been a source of friction in a state that was home to two of the most deadly mass shootings in U.S. history. A turning point came on July 20, 2012, when a gunman walked into a late-night show at a movie theater in Aurora, killing 12 people and leaving more than 70 injured. A few short months later, the wounds of the Columbine High School massacre of 1999 were reopened as victims watched families in Newtown, Conn., go through an all too familiar struggle.

A Quinnipiac poll released last month found that 82 percent of Colorado voters supported expanded background checks for gun sales. But respondents were split down the middle on the 15-round magazine limit.

Proponents of the recall were defiant in their victory over Morse as results became clear Tuesday night.

"After tonight, no one should underestimate the political potency of the gun control debate," Republican strategist Kurt Bardella, who served as a communications consultant on the recall, said in a statement.

Mark Glaze, a spokesman for Bloomberg's anti-gun violence group Mayors Against Illegal Guns, cautioned against applying too many conclusions from Colorado to the broader gun debate.

"There's an understandable impulse to extrapolate the Colorado results into a national trend. The only trend here is the NRA wasn't able to defeat as many legislators as it went after," Glaze told The Huffington Post in an interview. "A national coalition against gun violence provided counterweight to the NRA in these recalls for the first time. The NRA cherry-picked the most vulnerable legislators in Colorado, including a Senate president who represents one of the most conservative congressional districts in the country."

A statement put out by the National Rifle Association Political Victory Fund lauded Morse's defeat as "historic."
The people of Colorado Springs sent a clear message to the Senate leader that his primary job was to defend their rights and freedoms and that he is ultimately accountable to them -- his constituents, and not to the dollars or social engineering agendas of anti-gun billionaires.
This story was updated with statements from the NRA. Reported by Huffington Post 13 hours ago.

Aurora competitors team with UnitedHealth in new ACO

$
0
0
Four southeast Wisconsin hospitals systems have set aside their competitive differences to partner with the state’s largest health insurer UnitedHealthcare and challenge market leader Aurora Health Care in the new movement toward lower costs and higher quality. Columbia St. Mary’s, Froedtert Health, Wheaton Franciscan Healthcare and the Medical College of Wisconsin are collaborating in the new Quality Health Solutions affordable care organization (ACO). Also participating from the Fond du Lac… Reported by bizjournals 12 hours ago.

Two Colo. lawmakers recalled over gun control support

$
0
0
Lose first legislative recall election in state history for backing tougher gun laws after Aurora, Newtown mass shootings Reported by CBS News 11 hours ago.

Colo. lawmakers lose recalls over gun laws support

$
0
0
Colorado voters ousted two state lawmakers Tuesday in first-ever recall elections that came in reaction to the Democrats' support for tougher gun laws in the aftermath of last year's mass shootings in Aurora and... Reported by WTHR 10 hours ago.

Community College of Aurora Sees 70% Increase in Student Participation in Workforce Investment Act

$
0
0
Students at CCA, a Colorado community college, are drawn to the ability to increase knowledge base, skills, job prospects and financial stability through longstanding government option for unemployed, underemployed.

Denver, CO (PRWEB) September 11, 2013

Navigating a fickle job market can be overwhelming, particularly to those who may not know all the tools available in attempting to improve their stock or simply rejoin the workforce.

Barbara Lindsay, coordinator of Career Services at CCA, one of the Colorado community colleges, suggested that the institution continues to get tangible results under the auspices of the federal Workforce Investment Act, in concert with periodic job fairs that bring potential internships, part-time and full-time opportunities right to students’ doorsteps.

“More people should investigate it because even if they don’t need 18 months of training, there are other components of the Workforce Investment Act that allows them to connect in intentional ways to the job market,” Lindsay said.

At CCA, student participation -- due to a targeted informational campaign --in affiliated workforce programs has increased 70 percent in the last year, mainly due to WIA.

A study by Economic Modeling Systems, Inc., as recently as 2011 showed the tangible results of extra education within the college’s market, too, with earnings increasing $13,800 to $52,800 for people earning an associate’s degree at the career midpoint over those with solely a high school degree.

WIA, in particular, provides not just funding of education but a possible reinvention tool for those seeking a change. Participants can take classes for two terms, graduate with a certificate, and return to their employers better prepared for the tasks at hand, or be better positioned to locate a job if dealing with short- or long-term unemployment.

This conduit to a better work experience is applicable not only at Community College of Aurora, but is applicable to community colleges around the nation. Those who know how can use the government program to their advantage, while at the same time, helping fill jobs that are – and will be - necessary in the 21st century workforce.

“People are getting aware of the training dollars. They are doing a better job finding the resources available to them and we’ve done better letting them know that these types of programs are available for them,” Lindsay said.

Those already employed with ‘soft skills’ can obtain a new set of skills to enhance marketability in a wide variety of areas, such as full-charge bookkeeping, administrative support within health care, or roles in the computer industry can strengthen their resumes within a year and have their college expenses absorbed by the WIA program.

Up to 18 months of tuition and fees related to self-improvement in growth fields are available to qualified applicants. Unemployed or underemployed employees can benefit by receiving the training necessary to get back on the payroll. One such example would be receiving STEM training, given a recent report that showed that those jobs should increase by 18 percent by 2018.

“I always tell them to combine their previous work experience with whatever their new skill is going to be to repackage themselves to be employable.

Community College of Aurora works in concert with workforce development centers in surrounding counties (Adams, Arapahoe/Douglas, Denver) to connect returning, or first-time students, to employment opportunities in their own community. The workforce center connects students to employers and a computerized job bank, while offering help on networking, resumes, cover letters and more.

“It’s a win-win-win,” Lindsay said. “It’s good for the workforce centers, the employers that both we and the workforce centers work with, and the students.”

Lindsay advised that even those currently employed “look constantly, connect regularly to people at all times that can help, and use every resource available to you, because even while you have a job, if you don’t do that, it’s harder to start from scratch.”
Truth is, looking for employment can be a full-time job in itself.

“Connecting to work force centers, on campus to career centers, going on LinkedIn and making sure you have a profile that people will be engaged in. It’s about connecting with people and resources.”

###
About CCA
Community College of Aurora has campuses at CentreTech and Lowry in the greater Denver area. Equipped with the latest technologies, CCA allows students to study new and traditional programs, while also offering Colorado online courses and degrees. CCA’s service community spans 325,000 people in a 350-square-mile area and CCA’s student population reflects that diversity. The college provides lifelong educational opportunities, prepares the current and future workforce, and promotes excellence in teaching, learning and service. Reported by PRWeb 10 hours ago.
Viewing all 17855 articles
Browse latest View live


Latest Images