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Fresenius Kabi Receives FDA 510(k) Clearance for the Aurora™ Xi Plasmapheresis System

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Fresenius Kabi Receives FDA 510(k) Clearance for the Aurora™ Xi Plasmapheresis System LAKE ZURICH, Ill.--(BUSINESS WIRE)--Fresenius Kabi announced today it has received FDA 510(k) clearance for the Aurora™ Xi Plasmapheresis System. Fresenius Kabi is a global health care company that specializes in medicines and technologies for infusion, transfusion and clinical nutrition. “The Aurora Xi system features a proprietary filtration-separation method that enables the faster collection of Source Plasma. The system helps to improve plasma center efficiency and the overall experience fo Reported by Business Wire 1 hour ago.

Aurora officer won’t be charged for shooting man holding pellet gun in McDonald’s bathroom, Adams County DA says

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An Aurora Police Department officer will not be charged with a crime in connection with the May shooting of a man brandishing a pellet gun inside a McDonald's bathroom. Reported by Denver Post 18 hours ago.

Trump's Scandal Could Cost House Republicans Big

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WASHINGTON ― Donald Trump’s lewd comments about women present him with a tough challenge roughly one month before Election Day, and it’s also landed House Republicans in trouble.

The Democratic Congressional Campaign Committee pounced on the GOP presidential nominee’s hot mic incident late Friday night, recognizing that the problem Trump presents House Republicans with has suddenly been exacerbated.

“We have never taken our foot off the gas with tying Republicans to Trump,” DCCC national spokeswoman Meredith Kelly told The Huffington Post Friday night, “and these comments prove why that strategy was right on the money.”

The DCCC’s thinking has always been that Republicans were in a bind with Trump. Support him and you could ostracize swing voters. Resist him and you signal to Republicans that they should stay home. Plus, there’s a whole segment of Trump supporters who are truly excited about the brash businessman. Stand up to him and you risk GOP voters skipping over your name.

But House Republicans seemed confident recently that they weren’t suffering the down-ballot effects that Democrats had expected. “We’re in a much stronger position than anybody thought,” House Majority Leader Kevin McCarthy (R-Calif.) told reporters on Sept. 26, adding that he hadn’t seen a race that had a single GOP incumbent down.

That is almost certainly an exaggeration. Look no further than Rep. Bob Dold’s Illinois district, or Rep. David Jolly’s Florida 13th, or Rep. Frank Guinta’s New Hampshire 1st district. But Republicans no doubt were feeling better than they had expected, largely because they were able to avoid the Trump tarnish. Voters just weren’t connecting Trump with their incumbent GOP Representative.

That was, until Friday.

With Trump’s remarks about women coming to light ― comments that, more than just being vulgar, suggest Trump has made unwanted sexual advances on women ― there seems to be a real turn in this election.

Already, three House Republicans have either withdrawn their endorsement or called on Trump to drop out of the race. Now that those members have taken a stand, there could be other Republicans who feel the need to revoke their support. Which is not to say those Republicans can just escape the Trump taint.

As another DCCC spokesman, Tyler Law, said early Saturday after news that vulnerable Rep. Mike Coffman (R-Colo.) was calling on Trump to abandon his presidential bid, “this political charade changes nothing.”

“Donald Trump’s true character became clear when he attacked a Gold Star family, said he knew more about the Islamic State militant group than Army generals, called women slobs and pigs and labeled Mexicans as rapists and murderers. Coffman has had more than enough time to find some moral conviction and stand up to Trump,” Law said, conveniently laying out the game-plan against Republicans who suddenly find the courage to stand up to Trump.

Coffman’s case is particularly poignant. He’s in a heavily Latino district. For Colorado, at least, that looks apt to support Democratic presidential nominee Hillary Clinton. He had already expressed unease with Trump, suggesting that he couldn’t endorse the GOP nominee, but that unease awkwardly manifested itself Friday night.

After his Democratic challenger, Morgan Carroll, slammed him for his silence, Coffman told the Aurora Sentinel newspaper that Trump’s comments on women were “deeply offensive and disgusting.” Hours later, with the paper noting that Coffman still hadn’t said who he’d vote for, Coffman upgraded his discontent by calling on Trump to “step aside.”  

And this seems like the major shift. 


Not only are these comments beyond the pale, but their timing is particularly troubling for House Republicans.

Republicans are suddenly going to have to account for their Trump support, even their lack of opposition to the former reality TV personality, in a more direct way. House Republicans may finally own Trump. And if, as many expect, the nominee’s support craters because of these comments, Republicans would be facing a difficult climate anyway ― forget a lack of split-ticket voters.

As another Democratic aide said late Friday night, “Who comes out unscathed in this?”

The DCCC seems to think what makes these comments especially damaging ― on top of being vile ― is that voters are finally paying attention.

“Not only are these comments beyond the pale, but their timing is particularly troubling for House Republicans,” Kelly said. “Given the heightened voter engagement at this point in the cycle, we expect to see real impact from this story and Republican failure to denounce Trump as a result.”

Kelly added that Democrats are, of course, tailoring their message to the district. But the DCCC’s strategy has always been to get earned media with Trump, and use paid money on whatever issue polls best in each area.

For most of these races, Democrats had thought Trump would be a weight on the GOP ticket, particularly in suburban, educated, and affluent districts. But there had been plenty of concern that the Democratic Party had put up too many weak candidates who couldn’t get within striking distance of incumbent Republicans, and that Trump wasn’t the anvil that strategists expected, especially in Rust Belt areas.

Still, almost everyone expected the Democrats to pick up seats. It was just that gains of 10 seats, maybe 15, were looking far likelier than 20, 25, or the 30 needed for them to take back the majority.

Democrats were looking at the map, and even with more than 50 seats held by Republicans that have a Partisan Voting Index score of R+4 or better ― with seven seats actually having a Democratic PVI ― the Cook Political Report was rating two-thirds of those seats as either “Safe Republican,” “Likely Republican,” or “Lean Republican.”

But now, if Clinton actually does wipe the floor with Trump, there are a whole host of other seats that could suddenly come into play. Seats like Kevin Yoder’s Kansas district, which is an R+5. Or an open seat race in Virginia’s 5th district, another R+5 that wasn’t really on anyone’s radar.

And those races that were once tilting toward Republicans could suddenly swing in the direction of the Democrats. Twenty seats suddenly doesn’t look so far-fetched, and who controls the House come the 115th Congress isn’t such a ridiculous question anymore, if this scandal turns out to be as big of a deal as the early traction seems to indicate.

This could be the scandal that finally lands on Trump. And House Republicans who saw no signs of a Democratic wave could get pulled down by the undertow.

Editor’s note: Donald Trump regularly incites political violence and is a serial liar, rampant xenophobe, racist, misogynist and birther who has repeatedly pledged to ban all Muslims ― 1.6 billion members of an entire religion ― from entering the U.S.

-- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website. Reported by Huffington Post 2 hours ago.

Batavia Girls Injured in Fatal Aurora Crash

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Batavia Girls Injured in Fatal Aurora Crash Patch Batavia, IL -- Police say the man who caused the crash was driving under the influence. Reported by Patch 21 hours ago.

Aurora police searching for possible kidnapping, assault suspect

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The Aurora Police Department Major Crimes Unit issued an alert early Saturday evening as it continues to investigate a possible kidnapping and assault that occurred in the 500 Block of Sable Blvd. Reported by Denver Post 13 hours ago.

Apple Self Storage Fundraising for the ABLE Network

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With every new storage unit rental between October 1st and November 25th, Apple Self Storage will donate $10 to The Able Network. The charity promotes healthier, more rewarding lifestyles for individuals with intellectual disabilities.

(PRWEB) October 10, 2016

In the spirit of community, Apple Self Storage will be donating a portion of the proceeds from every new storage unit rental from October 1st and November 25th to the ABLE Network, a non-profit organization that assists young adults with intellectual disabilities through a series of support programs.

Last year, Apple Self Storage facilities launched the company-wide fundraising event and on November 21, 2015, Apple Self Storage donated $10,510. This year, their goal is to surpass that.

With every new rental between October 1st and November 25th Apple Self Storage will donate $10 to The Able Network.

The ABLE Network works with adults with intellectual disabilities and strives to instill a sense of confidence and autonomy in all program participants, providing workplace training and recreation opportunities that also create positive impacts in the surrounding communities. Apple Self Storage recognizes the valuable work done by the ABLE Network as Doug, a 23 year old participant (who many of you know), has been working with Apple at our head office for almost 2 years and is absolutely awesome.

About Apple Self Storage

Providing safe, secure and convenient storage units in 25 locations, Apple Self Storage strives to deliver a uniformly positive experience across its many facilities. The family-owned company has established close bonds with the communities in which it operates, and regularly pursues opportunities to assist organizations that enrich those communities.

About the ABLE Network

Located in Aurora, Ontario, the ABLE Network assists young adults with intellectual disabilities who are interested in personal growth and development. Program participants receive guidance in healthy living while also being immersed in natural job scenarios designed to boost their confidence and self-sufficiency. The charity operates with the goal of creating opportunities that make it possible for people with intellectual disabilities to participate fully in society, for the betterment of both the individual and their community. Reported by PRWeb 9 hours ago.

KOCCA to Launch Korean Pavilion at Brand Licensing Europe 2016 Held in London from Oct 11 to 13

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- KOCCA to introduce Korean animation characters to penetrate European market

- KOCCA to support 14 Korean animated character enterprises such as CJ E&M and LINE FRIENDS through commercial promotion and consulting about character export and various business activities.

SEOUL, South Korea, Oct. 10, 2016 /PRNewswire/ -- The South Korean Ministry of Culture, Sports and Tourism and Korea Creative Content Agency (KOCCA) have announced that they will jointly launch the Korean pavilion at Brand Licensing Europe 2016, which will take place at Olympia London from October 11-13.

Brand Licensing Europe is the biggest licensing event in Europe and welcomes over 300 exhibitors from 63 countries in addition to major retailers, merchandisers and agencies. It is widely recognised as the European version of the Licensing Expo held in Las Vegas.

This year, the Korean pavilion will present a total of 13 leading animation and character production companies in Korea such as:

· CJ E&M: produced animation 'Rainbow Ruby'
· LINE FRIENDS: produced mobile messenger character 'LINE Friends'
· Red Rover: produced 3D animation 'Bubble Bubble Marine'
· Booze: produced 'Bbugga'
· Youngsilup: produced 'Ddobot'
· Aurora: produced 'Yoohoo with Friends'

They will perform various activities including buyer meetings to stimulate export business for Korean characters.

As the five leading Korean animation companies, KOCCA will work with Redrover, Roivisual, Booze, Aurora World and CJ E&M -- all of whom enjoyed notable success at Brand Licensing Europe in 2015 -- to offer commercial, media and licensing support to help promote the reputation of Korean content in the EU market.  

KOCCA has also reinforced business activities in advance to support the setting up of customized marketing and business strategies for Korean companies who participate in the exhibition, by providing market data, a list of major buyers and character licensing industry trends of market leading countries in Europe.

South Korea's Ministry of Culture, Sports and Tourism and KOCCA are also planning to assist exhibitors in promoting more efficient business modes by providing various materials such as meeting space and a publishing and distribution PR guidebook.

Photo - http://photos.prnewswire.com/prnh/20161007/416352LOGO Reported by PR Newswire Asia 9 hours ago.

Aurora Health Care brings Chicago to Milwaukee for gala: Slideshow

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Aurora Health Care went south of the Illinois-Wisconsin border to get its surprise musical guest for its annual gala bringing in the legendary rock band Chicago to perform for more than 800 guests Saturday. Check out the attached slideshow put together by Milwaukee Business Journal freelance photographer Kenny Yoo to see photos of the band perform and of the popular event. The sold-out black-tie event, which was called "Just Like You," was held at the BMO Harris Bradley Center and raised a record… Reported by bizjournals 5 hours ago.

Alienware Aurora (2016)

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The Alienware Aurora is a more compact gaming desktop than some of the behemoths we've tested lately, but it's more than capable of handling VR and fluid gameplay on one or more 4K monitors. Reported by PCMag.com 1 hour ago.

Meth-dealing daughter of British aristocrat shot dead amidst Philippine president's war on narcotics was murdered by her ex-boyfriend over drug money, police believe

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Meth-dealing daughter of British aristocrat shot dead amidst Philippine president's war on narcotics was murdered by her ex-boyfriend over drug money, police believe Police in Manila say they are close to linking the murder of Aurora Moynihan, daughter of Lord Tony Moynihan with a 'high-level' drug supplier who is believed to be her ex-boyfriend. Reported by MailOnline 5 hours ago.

Former Moog exec, 2 others join Astronics board

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Astronics has expanded the head count on its board of directors, adding three members. That brings the number of directors to nine, eight of whom are independent, according to the East Aurora-based (NASDAQ: ATRO) manufacturer of products for the aerospace, defense, and semiconductor industries. The new additions are: Jeffry Frisby, Warren Johnson and Neil Kim. Board president Kevin Keane noted the three all have experience with aerospace and semiconductor companies. In a statement Keane said,… Reported by bizjournals 3 hours ago.

Condrey Corporation Listed as a Representative Vendor in Gartner 2016 Market Guide for File Analysis Software

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Included for Its products, Senergy, Galileo, and Aurora in the Governance, Efficiency and Optimization, as well as Risk Mitigation Use Cases Reported by Marketwired 58 minutes ago.

Aurora Exchange enlists Maiden Life and Mangopay for P2P lending platform

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Aurora Exchange, a consumer loans exchange for responsible borrowers announced two major partnership... Reported by Finextra 1 hour ago.

5th Annual Celebration of Sagrantino Month Returns to New York City, Chicago and San Francisco

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In Partnership with Eataly, Sagrantino Month Serves as the Centerpiece of a Multi-Year Campaign to Support Growing Popularity of Umbria’s Signature Wines

New York, NY (PRWEB) October 11, 2016

The Montefalco Consortium, the entity that oversees the historic Montefalco wine producing region of Italy, announces its fifth annual Sagrantino Month to be held this November. Montefalco, a region in Umbria regarded for distinctive winemaking, will be showcasing the wines of nine producers, as well as introducing new initiatives as part of a multi-week program created to educate consumers, press and trade.

Amilcare Pambuffetti, President of the Montefalco Consortium, stated, “Sagrantino will come to America once again thanks to this exciting promotion. The tour will begin in Canada with events in Toronto and Montreal, and will arrive in the US on November 7th, with stops San Francisco, Chicago, and New York. This is not just a tour, but an important series of events that will help us to increase exports of the wines of Montefalco and to make trade and consumers alike fall in love with Sagrantino.” He went on the say that “We strongly believe in this project, which continues to help spread the word about Montefalco and Sagrantino throughout the world.”

The US events will kick off on November 7th with a week of tastings and seminars, all with the theme Savoring Sagrantino: Discover Umbria's Indigenous Varieties. Beginning on Friday, November 11th, consumer tastings will be held at two Eataly wine shop locations, the Flatiron district in New York City and in Chicago, and will continue through the first week of December. All are welcome to taste the essence of Umbria through the indigenous varieties from which winemakers produce these exemplary wines.

In addition to tastings open to the public, the promotion will include seminars for press and trade and wine-by-the-glass programs at all of Eataly’s restaurants. Eataly’s diligence in familiarizing American consumers with authentic Italian cuisine and the Montefalco Consortium’s commitment to excellence in Umbrian wines is a natural partnership for Sagrantino Month.

The high quality of these wines can be attributed to a long history of perfecting the art of winemaking. The name ‘Sagrantino’ comes from the word ‘Sacrament’ as the grape was cultivated by monks during medieval times to produce a sweet wine used for religious rites. The Sagrantino variety thrives only on the hills of Montefalco and its surrounding area, where the indigenous grape achieves its highest expression. Montefalco white varieties such as Grechetto and Trebbiano Spoletino are also indigenous to Umbria and are enjoying increased popularity as winemakers in the region focus on making excellent wines from native grapes.

In addition to events at Eataly, consumer dinners will be held at participating restaurants in: San Francisco (54 Mint, La Ciccia, Chiaroscoro, A 16, Milano, Ideale Ristorante); Chicago (The Charlatan, Piccolo Sogno, Balena); and New York (Aurora Soho, Emporio NY, Peasant NY, Il Buco, Il Buco Alimentari & Vineria, Tarallucci e Vino, Obicà NY Flatiron) featuring the wines of Montefalco and offering traditional Italian fare to be paired with each wine variety. Winemakers will be present at select dinners to discuss the wines.

Nine wineries will participate in Sagrantino Month: Antonelli San Marco, Arnaldo Caprai, Viticoltori Colpetrone, Perticaia, Scacciadiavoli, Tabarrini, Tenuta Castelbuono Lunelli, Terre de la Custodia, Viticoltori Broccatelli Galli.

Stay tuned for updates on specific events by visiting the Montefalco Consortium Facebook page (http://www.facebook.com/consorzio.montefalco) and website (http://www.consorziomontefalco.it/en/savoring-sagrantino.html). A full consumer tasting schedule is available online at Eataly NYC Flatiron (http://www.eataly.com/us_en/stores/nyc-flatiron) and Eataly Chicago (http://www.eataly.com/us_en/stores/chicago). Reported by PRWeb 22 hours ago.

Business Q&A: Legends Coffee, Aurora

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Legends Coffee brings specialty coffee to the 'burbs of southeast Aurora. Reported by Denver Post 17 hours ago.

Colorado Clinic Welcomes New Board Certified Pain Management Doctor Paul Leo MD

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Colorado Clinic welcomes the addition of Board Certified pain management doctor Paul S. Leo, MD. He is Board Certified in Anesthesiology and Board Certified and fellowship-trained in Pain Management.

Boulder, Colorado (PRWEB) October 12, 2016

Colorado Clinic welcomes the addition of Board Certified pain management doctor Paul S. Leo, MD. He is Board Certified in Anesthesiology and Board Certified and fellowship-trained in Pain Management. He has been practicing in Colorado since 1994.

Dr. Leo received his Bachelor of Arts Degree in Physics with concentrations in Science and German Literature at Cornell University in Ithaca, NY. He earned his Doctor of Medicine degree at State University of New York at Downstate Medical Center in Brooklyn, NY. After 2 years of surgical training, he completed an Anesthesia Residency and Pain Management Fellowship at The Mount Sinai School of Medicine in Manhattan. Following 2 years of group practice in NYC and passing his Boards, he back-packed on other continents and he settled in Golden in 1994.

He has worked in a variety of settings including: community and rural hospitals, teaching programs and at Level I Trauma Centers in Brooklyn, the Bronx, and Denver (at St. Anthony’s Central Hospital).

He understands that pain affects each person differently and works to find the best solution to each patient’s problem. Dr. Leo believes in a multi-disciplinary approach, combining complimentary therapies, medications and interventional procedures when necessary. The goal is improved function, decreased pain and overall improvement in quality of life.

Dr. Leo has performed thousands of procedures including implantation of intrathecal pumps, spinal cord stimulators, radiofrequency and cryotherapy ablations, cervical and lumbar spinal injections – including epidural steroids and facets, joint injections, trigger points and dry needling. He will also be using regenerative medicine techniques including PRP and stem cell injections. He is qualified in medically assisted treatment (MAT) for opiate addiction in conjunction with qualified therapy programs.

Dr. Leo is currently accepting new patients at Colorado Clinic’s Locations in Boulder and Aurora. Visit http://coloradoclinic.com for more information and to Schedule an appointment, please call: 303-444-4141. Reported by PRWeb 9 hours ago.

Aurora Solar Technologies Provides Update on Business, Board Appointment and Option Grants

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*NORTH VANCOUVER, BRITISH COLUMBIA--(Marketwired - Oct. 12, 2016) -* Aurora Solar Technologies Inc. ("*Aurora*") ("*Company*") (TSX VENTURE:ACU)(OTCBB:AACTF)(FRANKFURT:A82), a leader in inline measurement and control technology for the photovoltaic manufacturing industry is continuing to progress on a number of significant multi-unit orders in Asia for its Decima in-line measurement and Veritas Visualization Software. "The technical decision-makers of producers of high efficiency mono-crystalline solar cells know that Aurora has the best available solution and, for these applications, we haven't lost a single technical evaluation to the competition," said Michael Heaven, Chief Executive Officer. He continued, "While we are subject to the speed at which our large, sophisticated customers implement decisions, we are progressing to the procurement phase and negotiating delivery schedules." Reported by Marketwired 3 hours ago.

Driver Loses Consciousness, Crashes into Aurora Retention Pond

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Driver Loses Consciousness, Crashes into Aurora Retention Pond Patch Oswego, IL -- The man was able to get out of the car and swim to safety with the help of an anonymous male bystander. Reported by Patch 2 hours ago.

Adding Oxidative Stress to FLT3 Inhibition Proves Promising Combination Against AML

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A University of Colorado Cancer Center study published today in the Proceedings of the National Academy of Sciences demonstrates the promise of adding drugs that increase oxidative stress to FLT3 inhibition, potentially paving the way for combination therapy directed at the disease.

AURORA, Colo (PRWEB) October 12, 2016

FLT3 inhibitors are a promising new class of drugs targeting acute myeloid leukemia (AML). However, these inhibitors alone tend not to result in long-term control of the disease. A University of Colorado Cancer Center study published today in the Proceedings of the National Academy of Sciences demonstrates the promise of adding drugs that increase oxidative stress to FLT3 inhibition, potentially paving the way for combination therapy directed at the disease.

“Essentially, we turned off every single gene in the genome, one by one, and asked which genes, when we turn them off, make AML cells more sensitive to these FLT3 inhibitors,” says Mark Gregory, PhD, research instructor in the CU School of Medicine Department of Biochemistry and Molecular Genetics, who works in the lab of CU Cancer Center Associate Director, James DeGregori, PhD.

The group found that many of these genes that were “synthetic lethal” with FLT3 inhibitors were involved in controlling a cell’s antioxidant response – basically, the genes discovered in this screen helped cells clear themselves of or protect against reactive oxygen species (ROS), the abrasive and potentially toxic byproducts of oxygen metabolism.

“At first we weren’t really clear why genes that control antioxidant response would be protecting these cells,” Gregory says. “Later we discovered that FLT3 inhibitors were inducing a great deal of oxidative stress. When you knock out a cell’s ability to deal with this oxidative stress, it becomes overwhelming and you kill a lot more of the leukemia cells.”

As a trip to the health food store’s supplement aisle implies, antioxidants may protect healthy cells. Unfortunately, this study shows that the body’s natural antioxidants may also protect the cells of acute myeloid leukemia from therapy.

Specifically, the group found that when they silenced the gene ATM, cells with this silenced gene were more susceptible to FLT3 inhibition. In fact, this gene works through another “downstream” gene, G6PD, and the group found that inhibiting G6PD had a similar sensitizing effect. Turning off ATM or G6PD impairs a cell’s ability to make glutathione, an important antioxidant that prevents damage from free radicals and peroxides associated with oxidative stress.

“When you turn off these genes, the AML cells are no longer able to make glutathione and you get a buildup of oxidative stress in the mitochondria, which triggers cell death,” Gregory says.

Because drugs to inhibit ATM and/or G6PD are not yet available, the group explored a creative alternative.

oxidative-stress-infographic“Rather than inhibiting these genes that protect against oxidative stress, we wondered what would happen if we combined FLT3 inhibition with drugs that induce even more oxidative stress,” Gregory says.

In both cell-based and mouse models of AML, adding a drug designed to induce oxidative stress resulted in far improved efficacy of FLT3 inhibition.

“We think this approach is very promising,” Gregory says. “There are many different pro-oxidative drugs in the clinic. Getting the right combination of one of these drugs with an FLT3 inhibitor could be very promising for AML.”

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DOI: 10.1073/pnas.1603876113 Reported by PRWeb 2 hours ago.

Roadside Safety Check Scheduled for This Weekend in North Aurora

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Roadside Safety Check Scheduled for This Weekend in North Aurora Patch Batavia, IL -- The Illinois State Police and the North Aurora Police Department will be conducting the safety check. Reported by Patch 20 hours ago.
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